Close up of turkey tail mushrooms growing in the wild
When to Take Turkey Tail Mushrooms: Timing and Benefits

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Turkey tail mushrooms (Trametes versicolor) are a popular medicinal fungus known for their immune-boosting properties and potential health benefits. As more people discover their advantages, questions arise about the optimal time to take them.

In this post, we will discuss when to take turkey tail mushrooms to maximise their benefits, with information sourced from credible academic sources.

When to Take Turkey Tail Mushrooms

1. Daily for Immune Support

For general immune support and overall wellness, it is best to take turkey tail mushrooms daily. A study conducted by the University of Minnesota (source) revealed that consistent, long-term use of turkey tail mushrooms can lead to a significant improvement in immune system function.

To maintain a healthy immune system, consider taking turkey tail mushrooms in the morning or afternoon, as a daily supplement.

2. During Cold and Flu Season

Turkey tail mushrooms can be particularly beneficial during cold and flu season. Their beta-glucans and polysaccharides support the immune system by activating white blood cells (source).

Taking turkey tail mushrooms during this period may help protect you from catching colds and flu, or reduce the severity and duration of these illnesses.

3. As an Adjunct to Cancer Treatment

Turkey tail mushrooms have shown potential in supporting the immune system of cancer patients undergoing chemotherapy and radiation treatments (source 3).

The Memorial Sloan Kettering Cancer Center has reported that taking turkey tail mushrooms can help improve the quality of life and survival rates for some cancer patients. However, it is crucial to consult with your healthcare provider before incorporating turkey tail mushrooms into your cancer treatment regimen.

4. For Digestive Health

Turkey tail mushrooms contain prebiotics, which help promote the growth of beneficial gut bacteria. Taking them regularly can support digestive health and maintain a balanced gut microbiome.

As a result, you may want to take turkey tail mushrooms with your meals or in-between them.


Turkey tail mushrooms offer several health benefits, and their optimal consumption depends on your individual needs and goals. For general immune support, daily intake is recommended, while increased intake during cold and flu season or as an adjunct to cancer treatment can provide additional benefits.

Lastly, taking them with or in-between meals can support digestive health.